Acknowledgements
The authors appreciate a patients, a investigators, and a investigate crew who done this hearing possible. The authors also appreciate Michelle Perate, MS, and Mary Whitman, PhD, of Janssen Scientific Affairs, LLC, who helped ready and contention a manuscript. The authors also appreciate a following institutional examination boards/ethics committees: China Medical University Hospital Instituted Review of Board 9 F, Taichung, Taiwan, Republic of China; Comité de Protection des Personnes Ile-de-France III, Hôpital Tarnier-Cochin 89, Paris, France; Commissie Medische ethiek outpost de Universitaire Ziekenhuizen KU Leuven/U.Z. Gasthuisberg, Leuven, Belgium; Ethikkommission der ärztekammer Westfalen-Lippe und der Medizinischen Fakultät der WWU Münster, Münster, Germany; Human Experiment and Ethics Committee, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Republic of China; HUS Helsingin ja Uudenmaan sairaanhoitopiiri, Medisiininen eettinen toimikunta, Biomedicum Helsinki, HUS, Finland; Institutional Review Board, Biomedical Research Institute, Seoul National University Hospital, Jongro-gu, Seoul, South Korea; Institutional Review Board, Dong-A University Hospital Clinical Research Center, Seo-Gu, Busan, South Korea; Institutional Review Board, Guro Hospital, Korea University Medical Center, Guro-Gu, Seoul, South Korea; Institutional Review Board, Hanyang University Hospital, Sungdong-Ku, Seoul, South Korea; Institutional Review Board, Pusan National University Hospital, Seo-Gu, Busan, South Korea; Institutional Review Board, Seoul St. Mary’s Hospital/The Catholic University of Korea, Seocho-gu, Seoul, South Korea; Joint Institutional Review Board. No. 201, Taipei, Taiwan, Republic of China; METC azM/UM Maastricht, Maastricht, The Netherlands; and Western Institutional Review Board, Olympia, WA, USA.
Funding
This investigate was saved by Janssen Research Development, LLC, and Merck/Schering-Plough.
Authors’ contributions
RDI done estimable egghead contributions to a investigate source and information interpretation, helped breeze and correct a publishing for critical egghead content, authorized a final chronicle to be published, and concluded to be accountable for all aspects of a work. XB done estimable egghead contributions to a investigate source and information interpretation, revised a publishing for critical egghead content, authorized a final chronicle to be published, and concluded to be accountable for all aspects of a work. KGAH done estimable egghead contributions to a investigate source and information interpretation, revised a publishing for critical egghead content, authorized a final chronicle to be published, and concluded to be accountable for all aspects of a work. JB done estimable egghead contributions to a investigate source and information interpretation, revised a publishing for critical egghead content, authorized a final chronicle to be published, and concluded to be accountable for all aspects of a work. AD done estimable egghead contributions to a investigate source and information interpretation, revised a publishing for critical egghead content, authorized a final chronicle to be published, and concluded to be accountable for all aspects of a work. DvdH done estimable egghead contributions to a investigate source and information interpretation, revised a publishing for critical egghead content, authorized a final chronicle to be published, and concluded to be accountable for all aspects of a work. SX done estimable egghead contributions to a information investigate and interpretation, helped to breeze and correct a publishing for critical egghead content, authorized a final chronicle to be published, and concluded to be accountable for all aspects of a work. BH done estimable egghead contributions to a investigate source and design, information acquisition, and information analysis/interpretation; helped to breeze and correct a publishing for critical egghead content; authorized a final chronicle to be published; and concluded to be accountable for all aspects of a work. All authors examination and authorized a final manuscript.
Competing interests
No nonfinancial conflicts of seductiveness exist for any authors. RDI has perceived consulting fees from Janssen, Merck, AbbVie, Amgen, and UCB. XB has perceived honoraria for talks and portion on advisory play as good as grants for studies from AbbVie, Amgen, Janssen Research Development, MSD (Schering-Plough), Novartis, Pfizer (Wyeth), and UCB. KGAH has perceived honoraria for educational lectures from Abbott, Janssen Research Development, MSD (Schering-Plough), Pfizer (Wyeth), and UCB. JB has perceived honoraria for talks and portion on advisory play as good as grants for studies from Celltrion, Amgen, Abbott, Roche, Bristol-Myers Squibb, Janssen, Novartis, Pfizer (Wyeth), MSD (Schering-Plough), Sanofi-Aventis, and UCB. AD has perceived investigate grants and has served on a advisory play of AbbVie, Amgen, Janssen, Pfizer, Novartis, and UCB. These intensity conflicts of seductiveness have been reviewed and managed by Oregon Health Science University. DvdH has perceived consulting fees from AbbVie, Amgen, AstraZeneca, Augurex, Bristol-Myers Squibb, Celgene, Chugai Pharmaceutical Co., Covagen, Daiichi Sankyo, Eli Lilly, Galapagos, GSK, Janssen Biologics, Merck, Novartis, Novo Nordisk, Otsuka, Pfizer, Roche, Sanofi-Aventis, UCB, and Vertex, and is executive of imaging rheumatology, Leiden University Medical Center. SX and BH are employees of Janssen Research Development, LLC
Ethics capitulation and agree to participate
The GO-RAISE investigate custom was reviewed and authorized by a institutional examination house or eccentric ethics cabinet during any site of this multicenter hearing and was conducted according to a beliefs of a Declaration of Helsinki and good clinical practice. All patients supposing created sensitive agree before a control of any study-related procedures.